Pakistan's recent tour to England was rocked by spot-fixing allegations which prompted a Scotland Yard investigation and the suspension of three of their players by the International Cricket Council.
Test captain Salman Butt, Mohammad Asif and Mohammad Aamer were charged for
violating various code of conduct during the Lord's Test against England in August, a controversy which Afridi said is a thing of the past.
"My players are professional and have put all the controversy behind them," Afridi said at the launching ceremony of the series in which Pakistan will also play five one-day internationals and two Tests.
The series is Pakistan's home series shifted to United Arab Emirates over security fears.
Afridi said the team has ample talent to counter the South Africans.
"We know we are without two of our best bowlers in Aamer and Asif," said Afridi of the two suspended bowlers. "But we still have ample talent to counter South Africa who are a very good side in the shorter form of the game."
South African captain Johan Botha agreed Pakistan will miss the talent of Asif and Aamer.
"You always miss quality players and surely Pakistan will miss the two (suspended) bowlers, but we too have injury problems in the team and when such things happen other players step in," said Botha.
Allrounder Jacques Kallis and fast bowlers Morne Morkel and Dale Styen were still recovering from various injuries and may not be able to play the first Twenty 20.
Botha hoped at least two of the three players will be available for the second Twenty 20, also to be played here on Wednesday.
"Playing Pakistan is always a great challenege and they knocked us out in two major Twenty20 matches," said Botha of Pakistan's wins over South Africa in the second and third World Twenty20 in 2009 and 2010 respectively
